4,4'-Dimethoxytrityl chloridebụ ihe dị ike nucleoside na nucleotide otu na-echebe ma na-ewepụ gị n'ụlọnga.
Otu okwu:DMT-Cl
Nọmba CAS:40615-36-9
Njirimara
Usoro ọgwụ
Ibu molekụla
Okpomọkụ nchekwa
Ebe Na-agbaze
Ịdị ọcha
Mputa
C21H19ClO2
338.82 g/mol
2 ~ 8 ℃
120-125 ℃
≥98%
kristal pink
Dị ka akụkụ dị mkpa nke ụdọ nucleic acid, nucleosides na nucleotides na-ekere òkè dị mkpa n'ịkwasa ozi mkpụrụ ndụ ihe nketa.Agbanyeghị, n'ihi mmeghachi omume kemịkalụ ha na mbibi dị mfe, nucleosides na nucleotides chọrọ reagents pụrụ iche iji chebe ha n'oge njikọ.DMTCl4'Dimethoxytrityl (DMTCl) bụ otu dị irè nke ukwuu na-echebe ma na-ewepụ ihe na-agbanwe agbanwe nke gbanwere nchebe nke nucleosides na nucleotides n'oge njikọ.
DMTCl bụ onye na-echebe hydroxyl nke na-ahọrọ nke na-emeghachi omume na ìgwè hydroxyl nke nucleosides na nucleotides n'oge njikọ iji mepụta otu nchebe nwa oge nke na-egbochi nucleosides na nucleotides ka ha na-emeghachi omume na kemịkalụ ndị ọzọ.A na-ewepụ otu nchekwa nchekwa nwa oge a ngwa ngwa mgbe njikọta, na-ahapụ nucleosides ma ọ bụ nucleotides dị ọcha.
N'ihi ezigbo reactivity na selectivity,DMTClA na-eji ya eme ihe dị ka otu nchekwa na mkpochapụ na njikọ DNA, RNA na acid nucleic ndị ọzọ.Ọ bara uru karịsịa maka njikọ oligonucleotide ebe achọrọ njikwa ziri ezi maka ọnọdụ nucleotide na usoro achọrọ.
Na mgbakwunye na ịrụ ọrụ dịka onye nchekwa na mkpochapụ otu, DMTCl bụ ihe nchekwa hydroxyl siri ike nke nucleosides na nucleotides.Ọ na-echebe ìgwè hydroxyl nke nucleosides na nucleotides site na oxidation, mbelata, na mmeghachi omume ndị ọzọ nwere ike imebi ha n'oge njikọ.
Na nchịkọta,DMTCl4 4' dimetoxytritylbụ ngwá ọrụ dị mkpa maka njikọ nke nucleosides na nucleotides.Mmeghachi omume ya dị oke mma, nhọrọ na ntụgharị na-eme ka ọ bụrụ ezigbo otu na-echebe ma na-ekpochapụ onye na-ahụ maka nchekwa hydroxyl maka DNA, RNA na njikọ nucleic acid ndị ọzọ.Ọ bụrụ na ịchọrọ nchekwa dị elu na ntụkwasị obi nke nucleosides na nucleotides n'oge njikọ, elela anya karịa DMTCl.
Oge nzipu: Jun-08-2023